Description

Reactivity:	Human, Mouse, Rat
Applications:	WB
Host Species:	Rabbit
Isotype:	IgG
Clonality:	Monoclonal antibody
Gene Name:	ectonucleoside triphosphate diphosphohydrolase 5 (inactive)
Gene Symbol:	GDF3
Synonyms:	PCPH; CD39L4; NTPDase-5
Gene ID:	957
UniProt ID:	Q9NR23
Clone ID:	24GB6110
Immunogen:	A synthesized peptide derived from human GDF3
Dilution:	WB 1:1,000-1:5,000
Purification Method:	Affinity purified
Concentration:	Lot dependent
Buffer:	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:	Store at -20°C. Avoid freeze/thaw cycles.

Background

The protein ENTPD5 encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases.

Images

Western blotting analysis using anti-growth differentiation factor 3 antibody (Cat#61186). Total cell lysates (30 μg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-growth differentiation factor 3 antibody (Cat#61186, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).

Western blotting analysis using anti-growth differentiation factor 3 antibody (Cat#61186). Growth differentiation factor 3 expression in wild type (WT) and growth differentiation factor 3 (GDF3) shRNA knockdown (KD) HeLa cells with 20 μg of total cell lysates. Hsp90 α serves as a loading control. The blot was incubated with anti-growth differentiation factor 3 antibody (Cat#61186, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody (Cat#201, 1:20,000) respectively. Image was developed using NaQ™ ECL Substrate Kit (Cat#716).

You may also be interested in: